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    CELEBRATING 10 YEARS

    A decade of longevity science. A new standard for your skin.

    Powered by our proprietary OS-01 peptide to target cellular aging at the source-for skin that looks and acts younger.

OUR APPROACH

Led by science, not hype

Rigorous R&D platform

End-to-end product development run by our in-house team of scientists.

Ongoing clinical studies

Conducted by independent, third-party research organizations.

Scientifically validated claims

Quantified by our proprietary MolClock and Skin Age Modeling methods.

Peer-reviewed publications

The gold standard for scientific research and in skin care.

    • 9+

      years of research

    • 900+

      peptides screened

    • 22+

      patents & publications

    • 12,000+

      5-Star Reviews

      OUR BREAKTHROUGH PEPTIDE

      OS-01: the new standard in peptide technology

      Think of OS-01 as a reset button for your skin, helping clear away the senescent cells that cause wrinkles, hyperpigmentation, and crepiness. As the first peptide scientifically proven to reduce cellular senescence in the skin, OS-01 does what other peptides can’t.

      WHAT CAUSES AGING?

      A main culprit: cellular senescence

      With age and exposure to environmental stressors, some cells enter a dysfunctional state known as senescence.

      Often called “zombie cells,” these cells release inflammatory factors that trigger nearby healthy cells to become senescent. As the body becomes less efficient at clearing them out, their buildup leads to:

      Increased Inflammation

      Suppressed Immune Function

      Accelerated aging

      • Lines and wrinkles

        Caused by a decline in collagen and elastin production.

      • Loss of elasticity

        Decreased elastin also contributes to lack of firmness.

      • Uneven skin tone

        Irregular melanin production leads to hyperpigmentation.

      • Rough texture

        Compromised skin cell renewal leaves a dry, uneven surface.

      • Loss of volume

        Linked to a decrease in hyaluronic acid, collagen, and elastin.

      • Thinning skin

        Slower cell turnover contributes to a weakened skin barrier.

        OUR LEADERSHIP TEAM

        Four scientists on a mission to redefine aging

        As scientists with PhDs in skin regeneration, stem cell biology, immunology, and bioinformatics, our journey began with a simple question: are any of the so-called anti-aging products on the market actually effective? To our surprise, most didn’t promote real rejuvenation. And evaluating them in the lab, we discovered some were even harmful at the cellular level.

        That’s when we rolled up our sleeves and got to work. More than 5 years of research and 900+ peptides later, we developed OS-01 – the first ingredient scientifically proven to reverse skin’s biological age. By targeting cellular senescence (one of the key drivers of skin aging) OS-01 switches off the damaged cells that contribute to lines, wrinkles, and sagging skin.

        But our vision was never just about looks. We started OneSkin to enhance how skin functions, so it stays healthier and more resilient as you age. Think of it as a long-term fitness plan for your skin. As your body’s largest organ, it’s crucial to make skin health a part of your overall approach to longevity — one that we believe also includes nutrient-dense foods, consistent exercise, stress management, and mental and emotional health.

        Good health is about feeling unstoppable, inside and out. That’s what drives us. And through our rigorous R&D process, peer-reviewed data, passion for life, and insatiable curiosity, we’re redefining the expectations around aging, empowering you with the knowledge to decide for yourself and enjoy life without limits.

        ONESKIN CO-FOUNDER & CEO

        Carolina Reis Oliveira, PhD

        Fascinated with biology from a young age, Carolina knew she’d have a future in science. A fearless leader with a passion for longevity and living life to the fullest, she embarked on an ambitious goal — to delay the onset of age-related diseases by targeting aging itself. This led her to earn degrees in stem cell biology and tissue engineering, and a doctorate in immunology. Then, determined to translate her academic achievements into real-world impact, Carolina left her native Brazil for Silicon Valley, co-founding OneSkin in 2016. As Chief Executive Officer, Carolina and her team spearhead research and development, creating molecules that target cellular aging, including their pioneering innovation, the OS-01 peptide.

        ONESKIN CO-FOUNDER & CHIEF SCIENTIFIC OFFICER

        Alessandra Zonari, PhD

        Alessandra isn’t your typical scientist. She’s a visionary with a passion for longevity, skin regeneration, and the occasional karaoke jam. Growing up in a close-knit family in Brazil, Alessandra saw her grandparents struggle with age-related diseases and soon became fascinated by the possibility of using stem cells to redefine the aging process. After earning degrees in biology and stem cell biology, and a doctorate in skin regeneration and tissue engineering, Alessandra joined OneSkin in 2017 as a founding member and Chief Scientific Officer. Her contributions include 20+ papers, 3 patents, and the development of their proprietary OS-01 peptide.

        CO-FOUNDER

        Mariana Boroni, PhD

        Mariana Boroni, PhD, co-founder, earned her Master’s degree in biochemistry, and her PhD in bioinformatics with an emphasis in genomics at the Federal University of Minas Gerais. Mariana did her post-doctoral at the Ludwig-Maximilians University of Munich in Germany, and worked as a visiting researcher at the University of Birmingham, England. Mariana is Head of the Bioinformatics and Computational Biology Lab at the Brazilian National Cancer Institute (INCA). Together with the OneSkin team, Mariana developed the company’s proprietary skin-specific DNAm age predictor. Mariana is co-inventor of four patents, and has published more than 20 peer-reviewed papers in scientific journals.

        CO-FOUNDER

        Juliana Carvalho, PhD

        Juliana Carvalho, PhD, earned her Master’s degree in biochemistry and immunology, and her PhD in molecular biology from the Federal University of Minas Gerais in Brazil. In 2015, Juliana joined the Catholic University of Brasilia as a professor of pathology, and in 2019, she joined the Faculty of Medicine at the University of Brasilia. As an advisor to students earning their Masters and PhD degrees in science at both the University of Brasilia and the Catholic University of Brasilia, Juliana guides the newest scientists of our generation. Juliana is co-inventor of four patents, and has published 34 peer-reviewed papers in scientific journals (and counting!).

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